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EphB3 Recombinant Rabbit Monoclonal Antibody (JE54-73)
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FIGURE: 1 / 4
EphB3 Antibody (MA5-36195) in IHC (P)
Immunohistochemical analysis of EphB3 in paraffin-embedded human prostate carcinoma tissue using a monoclonal antibody (Product #MA5-36195). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (1:200) for ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-36195
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JE54-73
Immunogen
Recombinant protein within Human Eph receptor B3 aa 80-220.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 0.05% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
EPHB3 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. The ephrin ligands and Eph receptors display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands. Ephs and ephrins play a significant role in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: embryonic kinase 2; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; human embryo kinase 2; tyrosine-protein kinase TYRO6
Gene Aliases: EK2; ETK2; HEK2; TYRO6
UniProt ID: (Human) P54753
Entrez Gene ID: (Human) 2049, (Rat) 287989
angiogenesis
urogenital system development
transmembrane receptor protein tyrosine kinase signaling pathway
axon guidance
axonal fasciculation
central nervous system development
cell migration
central nervous system projection neuron axonogenesis
corpus callosum development
regulation of cell-cell adhesion
neuron projection development
retinal ganglion cell axon guidance
substrate adhesion-dependent cell spreading
ephrin receptor signaling pathway
animal organ development
thymus development
digestive tract morphogenesis
regulation of axonogenesis
positive regulation of synapse assembly
palate development
dendritic spine development
dendritic spine morphogenesis
cell-substrate adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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