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Invitrogen
Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody (3F7A1)
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FIGURE: 1 / 2
Cytokeratin 6 Antibody (MA5-38024) in IHC (P)
Immunohistochemistry analysis of Cytokeratin 6 in paraffin-embedded human esophageal. Samples were incubated with Cytokeratin 6 Monoclonal antibody (Product # MA5-38024) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-38024
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
3F7A1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 465-564 of human Cytokeratin 6 (KRT6) (P48668)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.17 mg/mL
Amount
17 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: 5637, A-431
Immunogen sequence: YRKLLEGEEC RLNGEGVGQV NVSVVQSTIS SGYGGASGVG SGLGLGGGSS YSYGSGLGIG GGFSSSSGRA IGGGLSSVGG GSSTIKYTTT SSSSRKSYKH
Target Information
Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CK-6A; CK-6B; CK-6C; CK-6D; CK-6E; Cytokeratin-6A; Cytokeratin-6B; Cytokeratin-6C; Cytokeratin-6D; Cytokeratin-6E; K6A; K6B; K6C; Keratin K6h; Keratin, type II cytoskeletal 6A; Keratin, type II cytoskeletal 6B; Keratin, type II cytoskeletal 6C; Keratin-6A; Keratin-6B; Keratin-6C; Type-II keratin Kb10; Type-II keratin Kb12; Type-II keratin Kb6
Gene Aliases: K6A; K6B; KRT6A; KRT6B; KRT6C; KRT6D; KRT6E; KRTL1
Entrez Gene ID: (Human) 3853, (Human) 3854, (Human) 286887
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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