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Invitrogen
PAX3 Monoclonal Antibody (7D8G7)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-38590
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
7D8G7
抗原
Purified recombinant fragment of human PAX3 (aa: 142-203) expressed in E. Coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody has been tested in indirect ELISA.
靶标信息
Pax 3 (Paired Box 3) is a transcription factor that is involved in development of the peripheral nervous system, melanocytes, some vascular smooth muscle, and a number of other derivatives. It regulates neurogenesis in pre-migratory neural crest cells from the dorsal neural tube, and in myogenic progenitors in the presomitic mesoderm and the hypaxial somites. Alternative splicing results in isoforms having different C-termini.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HuP2; MGC120381; MGC120382; MGC120383; MGC120384; MGC134778; paired box gene 3; Paired box protein Pax-3; PAX3/FKHR fusion
基因别名: HUP2; Pax-3; PAX3; Sp; splotch
UniProt ID: (Mouse) P24610
Entrez Gene ID: (Mouse) 18505
negative regulation of transcription from RNA polymerase II promoter
neural crest cell migration
neural tube closure
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
nervous system development
heart development
muscle organ development
cell proliferation
positive regulation of cell proliferation
regulation of somitogenesis
cell migration
spinal cord association neuron differentiation
neural tube development
skeletal muscle cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
developmental pigmentation
neuron fate commitment
cardiac muscle cell differentiation
skeletal muscle organ development
mammary gland specification
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
