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Invitrogen
PLS3 Monoclonal Antibody (C4)
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FIGURE: 1 / 1
PLS3 Antibody (MA5-51120) in WB
Western blot analysis of PLS3 in various lysates. Samples were incubated with PLS3 monoclonal antibody (Product # MA5-51119) using a dilution of 0.2 µg/mL followed by HRP-Linked Caprine Anti-Mouse IgG secondary antibody at a dilution of 0.2 µg/mL. Lane 1: Porcine Liver lysate; Lane 2: Rat Cerebrum lysate; Lane 3: MCF7 cell lysate; Lane 4: Hela cell lysate.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-51120
Product Specifications
Species Reactivity
Human,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
C4
Immunogen
Recombinant Human PLS3 protein, Ala379-Val630 (Accession #P13797)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
20 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Phospholipid scramblases (PLS) translocate phospholipids bidirectionally between inner and outer leaflets of the plasma membrane and are implicated in apoptosis (1,2). Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: plastin 3 (T-isoform); Plastin-3; T-fimbrin; T-plastin
Gene Aliases: PLS3
Entrez Gene ID: (Pig) 100158187, (Rat) 81748
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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