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FIGURE: 1 / 13
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive Control: A549 cell lysate, A431 cell lysate, HeLa cell lysate, MCF7 cell lysate, SK-Br-3 cell lysate, BT-20 cell lysate.
Tissue Specificity: Low tissue specificity.
Subcellular Location: Membrane, Secreted, Cytoplasmic vesicle, secretory vesicle, acrosome membrane.
Sequence Similarities: No Cross with Mouse/Rat.
Predicted band size: 43 kDa.
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Breast epithelial antigen BA46; HMFG; Lactadherin; MFG-E8; MFGM; milk fat globule membrane; milk fat globule membrane protein; Milk fat globule-EGF factor 8; SED1
Gene Aliases: MFGE8
Entrez Gene ID: (Human) 4240
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