Invitrogen

AVEN Recombinant Rabbit Monoclonal Antibody (24GB6865)

Name: AVEN Recombinant Rabbit Monoclonal Antibody (24GB6865)
Brand: Invitrogen
SKU: MA5-56990
Availability: InStock

查看其他13个AVEN抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (3)

AVEN Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 3

AVEN Antibody (MA5-56990) in ICC/IF

Immunocytochemistry analysis of AVEN in HepG2 cells. Sample was incubated with AVEN monoclonal (Product # MA5-56989) antibody at a dilution of 1:1,000, followed by DAPI and Alexa Fluor 647. Protein abundance based on laser intensity and smart gain: Medium. Scale bar, 20 μm.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image AVEN Recombinant Rabbit Monoclonal Antibody (24GB6865)

产品信息

MA5-56990

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:5,000

免疫细胞化学 (ICC/IF)

1:100-1:1,000

流式细胞分析 (Flow)

1:200-1:2,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293F

分类

Recombinant Monoclonal

类型

Antibody

克隆号

24GB6865

抗原

A synthesized peptide derived from human AVEN (aa 113-126)

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Dry ice (international)

AB_3680016

靶标信息

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Aven is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that Aven functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that Aven impedes Apaf-1-mediated caspase activation. Higher levels of Aven mRNA are seen in patients with acute leukemia than in control patients, suggesting that Aven may be useful as a prognostic indicator in leukemia patients.

仅用于科研。不用于诊断过程。未经明确授权不得转售。