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Invitrogen
Pravastatin Recombinant Mouse Monoclonal Antibody (2B4)
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FIGURE: 1 / 1
Pravastatin Antibody (MA566359) in SDS-PAGE
SDS-PAGE characterization of Pravastatin under reducing conditions. Lane M: Protein marker (kDa); Lane PVT: Purified Pravastatin Recombinant Monoclonal (Product # MA566359). Pravastatin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-665.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA566359
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Mouse
/ IgG
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
2B4
Immunogen
Conjugate of PVT hapten and KLH.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Pravastatin is a member of the statin class of medications, primarily used to lower cholesterol and prevent cardiovascular disease. It functions by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver. Pravastatin is unique among statins due to its hydrophilic nature, which affects its absorption and distribution in the body, making it less likely to penetrate extrahepatic tissues. The gene location for HMG-CoA reductase is on chromosome 5q13.3, and the enzyme is a key target for pravastatin's lipid-lowering effects. Pravastatin is often compared to other statins like pitavastatin in clinical trials to evaluate its efficacy in lipid management. It is available in various dosages, commonly 40 mg, and is used in combination therapies for enhanced lipid-lowering effects. The biosimilar market for pravastatin is influenced by regulatory policies and market strategies, which are crucial for its adoption and development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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