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Invitrogen
17 alpha-hydroxyprogesterone Recombinant Mouse Monoclonal Antibody (5B10)
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FIGURE: 1 / 1
17 alpha-hydroxyprogesterone Antibody (MA566663) in SDS-PAGE
SDS-PAGE characterization of 17 alpha-hydroxyprogesterone under reducing conditions. Lane M: Protein marker (kDa); Lane 17-α-OH-P: Purified 17 alpha-hydroxyprogesterone Recombinant Monoclonal (Product # MA566663). 17 alpha-hydroxyprogesterone showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-373.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA566663
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Mouse
/ IgG
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
5B10
Immunogen
Conjugate of 17-alpha-OH-P hapten and KLH.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
7.2 mg/mL
Amount
200 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
17 alpha-hydroxyprogesterone, often abbreviated as 17-OHP, is a naturally occurring steroid hormone and a key intermediate in the biosynthesis of glucocorticoids, androgens, and estrogens. Structurally, it is a derivative of progesterone characterized by a hydroxyl group at the 17th carbon position, which plays a crucial role in its function and metabolism. In clinical contexts, 17-OHP serves as an important biomarker for diagnosing congenital adrenal hyperplasia (CAH), a genetic disorder affecting adrenal steroid synthesis. Elevated levels of 17-OHP in newborns are indicative of CAH due to 21-hydroxylase deficiency, leading to increased androgen production and the potential for abnormal sexual development. Measurement of 17-OHP is routinely performed in neonatal screening programs to promptly identify and manage this condition. Research into 17-OHP continues to advance understanding of steroidogenesis and its implications in various endocrine disorders, while also exploring therapeutic applications of synthetic analogs for reproductive health.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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