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Invitrogen
KV1.5 (KCNA5) Recombinant Rabbit Monoclonal Antibody (PSH12-30)
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FIGURE: 1 / 1
KV1.5 (KCNA5) Antibody (MA569993) in WB
Western blot analysis of KV1.5 (KCNA5) in various lysates. Samples were incubated with KV1.5 (KCNA5) monoclonal antibody (Product # MA569993) using a dilution of 1:2,000 in 5% NFDM/TBST at 4°C overnight followed by Goat Anti-Rabbit IgG - HRP Secondary Antibody at a dilution of 1:50,000 for 1 hour at room temperature. Lane 1: PANC-1 cell lysate(no heat) (15 µg/Lane); Lane 2: Mouse hippocampus tissue lysate (no heat) (20 µg/Lane); Lane 3: Mouse heart tissue lysate (no heat) (20 µg/Lane); Lane 4: Mouse liver tissue lysate (negative) (20 µg/La... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA569993
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
PSH12-30
Immunogen
Synthetic peptide within rat KCNA5 aa 249-298.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.2% ProClin 950
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: PANC-1 cell lysate, Mouse hippocampus tissue lysate, Mouse heart tissue lysate, Rat hippocampus tissue lysate, Rat heart tissue lysate.
Subcellular location: Cell membrane.
Target Information
In neurons voltage-dependent potassium channels are key determinants of the resting membrane potential and of membrane excitability, conditioning the frequency, and shape of action potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac potassium channel; insulinoma and islet potassium channel; KV1-5; MGC117058; MGC117059; Potassium (K+) channel protein alpha 5; potassium channel 1; potassium channel, voltage gated shaker related subfamily A, member 5; potassium voltage-gated channel, shaker-related subfamily, member 5; RCK7; RK4; unnamed protein product; voltage-gated potassium channel HK2; voltage-gated potassium channel protein Kv1.5; voltage-gated potassium channel subunit Kv1.5
Gene Aliases: ATFB7; HCK1; HK2; HPCN1; Kv1; KV1.5; PCN1
UniProt ID: (Human) P22460, (Rat) P19024, (Mouse) Q61762
Entrez Gene ID: (Human) 3741, (Rat) 25470, (Mouse) 16493
receptor binding
ion channel activity
voltage-gated potassium channel activity
delayed rectifier potassium channel activity
protein binding
outward rectifier potassium channel activity
protein kinase binding
alpha-actinin binding
voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization
voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
voltage-gated potassium channel activity involved in SA node cell action potential repolarization
scaffold protein binding
potassium channel inhibitor activity
action potential
response to hypoxia
ion transport
potassium ion transport
response to mechanical stimulus
regulation of membrane potential
response to hydrogen peroxide
regulation of insulin secretion
protein oligomerization
protein homooligomerization
negative regulation of cytosolic calcium ion concentration
potassium ion homeostasis
transmembrane transport
response to hyperoxia
membrane hyperpolarization
regulation of atrial cardiac muscle cell membrane repolarization
potassium ion transmembrane transport
atrial cardiac muscle cell action potential
membrane repolarization during bundle of His cell action potential
membrane repolarization during SA node cell action potential
regulation of heart rate by cardiac conduction
potassium ion export across plasma membrane
membrane repolarization during atrial cardiac muscle cell action potential
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of myoblast proliferation
Notch signaling pathway
regulation of vasoconstriction
negative regulation of potassium ion transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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