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Invitrogen
DEGS1 Polyclonal Antibody
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FIGURE: 1 / 2
DEGS1 Antibody (PA1-12912) in IHC (F)
Immunohistochemistry was performed on 4% paraformaldehyde-fixed frozen mouse retina tissue sections. Tissues were blocked in 3% normal goat serum + 0.3% Triton X-100 for 1 hour at room temperature and probed with a Degenerative Spermatocyte Homolog 1 (DSH1) polyclonal antibody (Product # PA1-12912) at a dilution of 1:500 overnight at 4°C. Tissues were washed extensively with PBS. Detection was performed usi... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-12912
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from the human DEGS1 protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control for this product is placenta lysate.
Target Information
The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4 ) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulation biosynthetic processing of the EGF receptor. Two splice variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell migration-inducing gene 15 protein; degenerative spermatocyte homolog 1; degenerative spermatocyte homolog 1, lipid desaturase; degenerative spermatocyte homolog, lipid desaturase; degenerative spermatocyte-like protein RDES; Delta(4)-desaturase; dihydroceramide desaturase; dihydroceramide desaturase 1; dihydroceramide desaturase-1; DSH1; membrane fatty acid (lipid) desaturase; membrane lipid desaturase; MGC5079; MIG15; migration-inducing gene 15 protein; putative fatty acid desaturase; retinol isomerase; sphingolipid 1; sphingolipid delta 4 desaturase; sphingolipid delta(4)-desaturase 1; transmembrane protein; unnamed protein product
Gene Aliases: DEGS; DEGS-1; Des-1; DES1; FADS7; HLD18; Mdes; MIG15; MLD
UniProt ID: (Human) O15121, (Mouse) O09005, (Rat) Q5XIF5
Entrez Gene ID: (Human) 8560, (Mouse) 13244, (Rat) 58970
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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