Invitrogen

CRYAB Polyclonal Antibody

Name: CRYAB Polyclonal Antibody
Brand: Invitrogen
SKU: PA1-20795
Availability: InStock

高级验证

1 篇参考文献

查看其他52个CRYAB抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (3)
高级验证 (1)

CRYAB Antibody in Immunohistochemistry (IHC)

图: 1 / 4

CRYAB Antibody (PA1-20795) in IHC

Immunohistochemical analysis of human brain cortex tissue stained with CRYAB Polyclonal Antibody (Product # PA1-20795) at 10 µg/mL.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

CRYAB Antibody — Antibody specificity was demonstrated by detection of differential basal expression of the target across tissues owing to their inherent genetic constitution. The expression was observed in Mouse Eye and Rat Eye and not in Mouse Heart, Mouse Skeletal Muscle, Mouse Lung and Mouse Liver using CRYAB Monoclonal Antibody (1A7.D5) (Product # PA1-20795) in Western Blot. {RE}

Immunogen image

Immunogen Image CRYAB Polyclonal Antibody

产品信息

PA1-20795

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:2,000

免疫组化 (IHC)

Assay-Dependent

免疫细胞化学 (ICC/IF)

1:200

免疫沉淀 (IP)

Assay-dependent

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Bovine, Hamster, Human, Mouse, Pig, Rabbit, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide: REEKPAVTAAPKK conjugated to KLH, corresponding to amino acids 163-175 of Human alpha B Crystallin.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Protein A

保存液

PBS with 50% glycerol

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2229846

产品详细信息

Expected to cross react with hamster and rabbit due to sequence homology. This antibody will not cross react with beta Crystallin nor alpha A Crystallin.

PA1-20795 detects a band ~22 kDa.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Lens proteins consist almost entirely of crystallins (about 95%). Crystallins are also found vertebrate skeletal muscle tissue. In the lens, their structural function is to assist in maintaining the proper refractive index of the lens. The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma. Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products-alpha-A and alpha-B. There are at least 5 different proteins comprising the beta-crystallins. The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens. Alpha-Crystallin comprises 40% of total lens protein composition. In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation. It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance. Alpha-B crystallin has been linked to Alexander's disease where it accumulates in brain cells of those afflicted.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: alpha B-crystallin; alpha crystallin B; Alpha(B)-crystallin; alpha-B-crystallin; Alpha-crystallin B chain; alpha-crystallin B chain-like protein; CryAB antibody; crystallin, alpha 2; crystallin, alpha B; crystallin, alpha polypeptide 2; Heat shock protein beta-5; heat shock protein CryAB; Heat shock protein family B member 5; heat shock protein HspB5; HspB5; HspB5 protein; P23; Renal carcinoma antigen NY-REN-27; Rosenthal fiber component

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基因别名: AACRYA; Crya-2; CRYA2; CRYAB; HSPB5; P23