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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Recommended positive controls: Human hepatocarcinoma tissue.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: matrix metallo protease; Matrix metalloproteinase-17; Membrane-type matrix metalloproteinase 4; Membrane-type-4 matrix metalloproteinase; MMP; MMP-17; MMPs; MT-MMP 4; MT4-MMP
基因别名: MMP17; MT4MMP
Entrez Gene ID: (Human) 4326