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Invitrogen
RAD17 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA1-4132
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues N(2) Q V T D W V D P S F D D F(15) of human RAD17.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA1-4132 detects human RAD17.
PA1-4132 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~66 kDa protein representing RAD17 in human heart lysate.
The PA1-4132 immunogen is a synthetic peptide corresponding to residues N(2) Q V T D W V D P S F D D F(15) of human RAD17.
靶标信息
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cell cycle checkpoint protein RAD17; FLJ41520; hRad17; RAD17 (Ser647); Rad17 like protein; RF-C/activator 1 homolog
基因别名: R24L; RAD17
Entrez Gene ID: (Human) 5884
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
