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Invitrogen
Acid Phosphatase 1 Polyclonal Antibody
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FIGURE: 1 / 1
Acid Phosphatase 1 Antibody (PA1-41703) in WB
Western blot analysis of Acid Phosphatase 1 in human liver lysate. Samples were incubated with Acid Phosphatase 1 polyclonal antibody (Product # PA1-41703) using a dilution of 1 µg/mL. 1) absence and 2) presence of immunizing peptide in human liver lysate.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-41703
Product Specifications
Species Reactivity
Bovine,
Human,
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A portion of amino acids 40-80 of human ACP1.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS with 0.2% gelatin
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-41703 detects Acid phosphatase 1, isoform b.
Suggested positive control: antigen standard for ACP1 (transient overexpression lysate), human liver protein, liver lysate.
Sequence identity: 86% with canine and 80% with rat proteins.
Target Information
Low molecular weight protein tyrosine phosphtases, including the human red cell phosphatase, HCPTP, are widely expressed cytosolic proteins of approximately 18 kDa that exist in distinct isoforms and are highly selective for phosphotyrosine over phosphoserine or phosphotyrosine. The HCPTP-A and HCPTP-B proteins expressed in human red cells and placenta are fast and slow forms of red cell acid phosphatase5. Like other tyrosine phosphatases, HCPTP is sensitive to inhibition by vanadate, and has a catalytic mechanism that involves formation of a cystinylphosphate intermediate6. The crystal structure of the bovine heart derived enzyme BHPTP shows a four-stranded central parallel b sheet with flanking a helices and an active site cysteine residue in the typical tyrosine phosphatase sequence context, CXXXXXR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acid phosphatase 1, soluble; Adipocyte acid phosphatase; HAAP betaÊ; LMW-PTP; LMW-PTPase; Low molecular weight cytosolic acid phosphatase; Low molecular weight phosphotyrosine protein phosphatase; MGC111030; MGC3499; phosphatase 1, soluble; ptpase; Red cell acid phosphatase 1
Gene Aliases: ACP1; LMW-PTP; LMW-PTPase
UniProt ID: (Bovine) P11064, (Pig) P81693
Entrez Gene ID: (Bovine) 280977, (Pig) 100737301
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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