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PA1-74159 detects Fibrinogen from rabbit samples.
PA1-74159 has been successfully used in ELISA applications.
The PA1-74159 immunogen is Fibrinogen from rabbit plasma.
Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。