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Invitrogen
Neuropilin 2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-95053
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human NRP2 (45-60aa YPQDYPSHQNCEWIVY).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue, Rat Testis Tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C) and SEMA3F protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F), and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Neuropilin-2; Vascular endothelial cell growth factor 165 receptor 2
Gene Aliases: 1110048P06Rik; Np-2; Np2; Npn-2; Npn2; Nrp2
UniProt ID: (Mouse) O35375, (Rat) O35276
Entrez Gene ID: (Mouse) 18187, (Rat) 81527
angiogenesis
neural crest cell migration
neuron migration
multicellular organism development
nervous system development
axon guidance
heart development
facial nerve structural organization
vestibulocochlear nerve structural organization
nerve development
gonadotrophin-releasing hormone neuronal migration to the hypothalamus
cell differentiation
ventral trunk neural crest cell migration
vascular endothelial growth factor signaling pathway
axon extension involved in axon guidance
negative chemotaxis
sympathetic ganglion development
trigeminal ganglion development
ganglion morphogenesis
semaphorin-plexin signaling pathway
sensory neuron axon guidance
sympathetic neuron projection extension
sympathetic neuron projection guidance
neural crest cell migration involved in autonomic nervous system development
semaphorin-plexin signaling pathway involved in neuron projection guidance
facioacoustic ganglion development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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