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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total LAS1L.
Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endoribonuclease LAS1L; Protein LAS1 homolog; Ribosomal biogenesis protein LAS1L
基因别名: 1810030A06Rik; 5830482G23Rik; LAS1L; MSTP060; RGD1565755
UniProt ID: (Mouse) A2BE28
Entrez Gene ID: (Mouse) 76130, (Rat) 296865