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Invitrogen
NPSR1 Polyclonal Antibody
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图: 1 / 3
NPSR1 Antibody (PA5-100959) in ICC/IF
Immunocytochemistry analysis of NPSR1 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with NPSR1 polyclonal antibody (Product # PA5-100959) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100959
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NPSR1(Accession Q6W5P4), corresponding to amino acid residues V233-F283.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total NPSR1.
靶标信息
May be active in signaling pathway in an autocrine or paracrine fashion in several tissues. Receptor for neuropeptide S, it may mediate its action, such as inhibitory effects, on cell growth. Involved in pathogenesis of asthma and other IgE-mediated diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein-coupled receptor 154; G protein-coupled receptor PGR14; G-protein coupled receptor 154; G-protein coupled receptor for asthma susceptibility; G-protein coupled receptor PGR14; Neuropeptide S receptor; vasotocin receptor
基因别名: 9330128H10Rik; GPR154; GPRA; MVTR; NPSR1; PGR14; RGD1564154; VRR1
UniProt ID: (Mouse) Q8BZP8
Entrez Gene ID: (Mouse) 319239, (Rat) 300458
signal transduction
G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
chemical synaptic transmission
eating behavior
positive regulation of release of sequestered calcium ion into cytosol
righting reflex
positive regulation of ERK1 and ERK2 cascade
negative regulation of eating behavior
negative regulation of defecation
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