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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total CNKR2.
This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CNK homolog protein 2; CNK2; CNK2A; CNK2B; connector enhancer of KSR 2; connector enhancer of KSR2; KSR2B; maguin; maguin-1; maguin-2; membrane-associated guanylate kinase-interacting protein; unnamed protein product
Gene Aliases: CNK2; KSR2; MAGUIN; MRXSHG
UniProt ID: (Human) Q8WXI2, (Rat) Q9Z1T4, (Mouse) Q80YA9
Entrez Gene ID: (Human) 22866, (Rat) 59322, (Mouse) 245684
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