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Invitrogen
Carboxypeptidase B2 Polyclonal Antibody
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Carboxypeptidase B2 Antibody (PA5-101496) in WB
Western blot analysis of Carboxypeptidase B2 in extracts from various samples. Samples were incubated with Carboxypeptidase B2 polyclonal antibody (Product # PA5-101496). Lane 1: Hepg2 cells (heat-shock treatment), blocked with antigen-specific peptides; Lane 2: Hepg2 cells (heat-shock treatment); Lane 3: Hela cells (heat-shock treatment).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-101496
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CPB2(Accession Q96IY4), corresponding to amino acid residues N256-Y306.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CPB2.
靶标信息
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: carboxypeptidase B-like protein; Carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase R; Carboxypeptidase U; CPU; pCPB; Plasma carboxypeptidase B; prepro-plasma carboxypeptidase B; TAFI; Thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor; unnamed protein product
基因别名: CPB2; CPU; PCPB; TAFI
Entrez Gene ID: (Human) 1361
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