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Carboxypeptidase E Polyclonal Antibody
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FIGURE: 1 / 3
Carboxypeptidase E Antibody (PA5-101497) in ICC/IF
Immunofluorescent analysis of Carboxypeptidase E in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with Carboxypeptidase E polyclonal antibody (Product # PA5-101497) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-101497
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CPE(Accession P16870), corresponding to amino acid residues P273-P323.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CPE.
Target Information
This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: carbocypeptidase E; Carboxypeptidase E; Carboxypeptidase H; CarboxypeptidaseE; CarboxypeptidaseH; CBPE; cobalt-stimulated chromaffin granule carboxypeptidase; CPE; CPH; Cph 1; Enkephalin convertase; epididymis secretory sperm binding protein; insulin granule-associated carboxypeptidase; Prohormone-processing carboxypeptidase; unnamed protein product
Gene Aliases: BDVS; CARBE; CPE; CPH; Cph-1; Cph1; fat; IDDHH; R74677
UniProt ID: (Rat) P15087, (Mouse) Q00493
Entrez Gene ID: (Human) 1363, (Rat) 25669, (Mouse) 12876
cardiac left ventricle morphogenesis
proteolysis
peptide metabolic process
cell communication
neuropeptide signaling pathway
protein localization
Wnt signaling pathway
protein processing
signaling
protein modification process
protein localization to membrane
peptide hormone processing
insulin processing
enkephalin processing
peptide catabolic process
negative regulation of branching morphogenesis of a nerve
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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