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Invitrogen
PP1 beta Polyclonal Antibody
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图: 1 / 3
PP1 beta Antibody (PA5-102349) in IHC (P)
Immunohistochemistry analysis of PP1 beta in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with PP1 beta polyclonal antibody (Product # PA5-102349) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-102349
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PPP1CB(Accession P62140), corresponding to amino acid residues S298-R327.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total PPP1CB.
靶标信息
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: epididymis secretory sperm binding protein Li 80p; MGC21657; myosin phosphatase; PP-1B; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX; PPP1CB; protein phosphatase 1, catalytic subunit, beta isoform; protein phosphatase 1, catalytic subunit, beta isozyme; protein phosphatase 1, catalytic subunit, delta isozyme; protein phosphatase 1-beta; protein phosphatase 1-delta; protein phosphatase-1a; Serine/threonine-protein phosphatase PP1-beta catalytic subunit; unnamed protein product
基因别名: 1200010B19; HEL-S-80p; MP; NSLH2; PP-1B; PP1B; PP1beta; PP1c; PP1Cbeta; PP1Cdelta; PPP1beta; PPP1CB; PPP1CD
UniProt ID: (Mouse) P62141, (Rat) P62142
Entrez Gene ID: (Human) 5500, (Mouse) 19046, (Rat) 25594
MAPK cascade
protein dephosphorylation
regulation of cell adhesion
circadian regulation of gene expression
regulation of circadian rhythm
entrainment of circadian clock by photoperiod
positive regulation of Ras protein signal transduction
carbohydrate metabolic process
glycogen metabolic process
regulation of glycogen biosynthetic process
regulation of glycogen catabolic process
cell cycle
rhythmic process
cell division
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
