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Invitrogen
POLD1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-102728
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human POLD1(Accession P28340), corresponding to amino acid residues C1058-W1107.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total POLD1.
靶标信息
This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3'-5' exodeoxyribonuclease; DNA polymerase delta 1, catalytic domain; DNA polymerase delta catalytic subunit; DNA polymerase delta, catalytic subunit; DNA polymerase subunit delta p125; DNA-directed DNA polymerase delta 1; POL D; Polymerase D
基因别名: 125kDa; POLD; POLD1
UniProt ID: (Rat) O54747, (Mouse) P52431
Entrez Gene ID: (Rat) 59294, (Mouse) 18971
nucleotide binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
3'-5'-exodeoxyribonuclease activity
3'-5' exonuclease activity
metal ion binding
4 iron, 4 sulfur cluster binding
nucleic acid binding
damaged DNA binding
nuclease activity
exonuclease activity
transferase activity
nucleotidyltransferase activity
hydrolase activity
iron-sulfur cluster binding
DNA metabolism protein
DNA synthesis involved in DNA repair
DNA catabolic process, exonucleolytic
DNA replication
DNA-dependent DNA replication
base-excision repair, gap-filling
nucleotide-excision repair, DNA gap filling
DNA replication proofreading
fatty acid homeostasis
DNA biosynthetic process
nucleic acid phosphodiester bond hydrolysis
cellular response to UV
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
