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Invitrogen
ADAM9 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102758
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ADAM9(Accession Q13443), corresponding to amino acid residues Y736-F786.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ADAM9.
Target Information
ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metallopeptidase domain 9 (meltrin gamma); a disintegrin and metalloprotease domain 9; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 9 (meltrin gamma); ADAM; ADAM 9; adam9; ADAMs; Cellular disintegrin-related protein; Disintegrin and metalloproteinase domain-containing protein 9; MDC 9; meltrin gamma; Meltrin-gamma; metalloendopeptidases; Metalloprotease/disintegrin/cysteine-rich protein 9; Myeloma cell metalloproteinase; OTTHUMP00000216481; OTTHUMP00000216484; OTTHUMP00000216485
Gene Aliases: ADAM9; AU020942; KIAA0021; MCMP; MDC9; mKIAA0021; MLTNG
UniProt ID: (Mouse) Q61072
Entrez Gene ID: (Mouse) 11502, (Rat) 290834
activation of MAPKK activity
proteolysis
membrane protein ectodomain proteolysis
cell adhesion
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
response to manganese ion
cell adhesion mediated by integrin
positive regulation of cell adhesion mediated by integrin
positive regulation of macrophage fusion
response to tumor necrosis factor
monocyte activation
response to hydrogen peroxide
positive regulation of protein secretion
positive regulation of membrane protein ectodomain proteolysis
PMA-inducible membrane protein ectodomain proteolysis
response to glucocorticoid
positive regulation of keratinocyte migration
response to calcium ion
cellular response to lipopolysaccharide
keratinocyte differentiation
cell-cell adhesion mediated by integrin
response to laminar fluid shear stress
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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