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Invitrogen
SLC27A1 Polyclonal Antibody
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FIGURE: 1 / 2
SLC27A1 Antibody (PA5-102890) in ICC/IF
Immunocytochemistry analysis of SLC27A1 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with SLC27A1 polyclonal antibody (Product # PA5-102890) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102890
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SLC27A1(Accession Q6PCB7), corresponding to amino acid residues S482-L532.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total FATP1.
Target Information
SLC27A1 is a protein coding gene. Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACSVL5FATP-1; arachidonate--CoA ligase; EC 6.2.1; fatty acid transport protein 1; FLJ00336; long-chain-fatty-acid--CoA ligase; MGC71751; solute carrier family 27 (fatty acid transporter), member 1; unnamed protein product; very long-chain acyl-CoA synthetase
Gene Aliases: ACSVL5; FATP; FATP-1; FATP1; Vlc27a1
UniProt ID: (Human) Q6PCB7, (Mouse) Q60714
Entrez Gene ID: (Human) 376497, (Mouse) 26457, (Rat) 94172
long-chain fatty acid-CoA ligase activity
long-chain fatty acid transporter activity
protein binding
biotin transporter activity
fatty acid transporter activity
efflux transmembrane transporter activity
very long-chain fatty acid-CoA ligase activity
identical protein binding
protein serine/threonine kinase activator activity
arachidonate-CoA ligase activity
oleoyl-CoA ligase activity
icosanoid transmembrane transporter activity
medium-chain fatty acid transport
long-chain fatty acid metabolic process
response to cold
positive regulation of triglyceride biosynthetic process
biotin transport
fatty acid transport
long-chain fatty acid transport
plasma membrane long-chain fatty acid transport
positive regulation of heat generation
response to insulin
adiponectin-activated signaling pathway
glucose import in response to insulin stimulus
long-chain fatty acid import
icosanoid transport
export across plasma membrane
biotin import across plasma membrane
lipid transport across blood brain barrier
transport across blood-brain barrier
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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