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Invitrogen
CEP63 Polyclonal Antibody
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FIGURE: 1 / 4
CEP63 Antibody (PA5-103728) in ICC/IF
Immunocytochemistry analysis of CEP63 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with CEP63 polyclonal antibody (Product # PA5-103728) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-103728
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CEP63(Accession Q96MT8), corresponding to amino acid residues D539-I589.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CEP63.
Target Information
CEP63 is a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membranous organelle that functions as the major microtubule-organizing center in animal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: centrosomal protein 63kDa; centrosome protein CEP63; unnamed protein product
Gene Aliases: 4921501M07; AL450317.13gm1; CD20R; D9Mgc41; D9Mgc48e; ET2; SCKL6
UniProt ID: (Human) Q96MT8, (Mouse) Q3UPP8
Entrez Gene ID: (Human) 80254, (Mouse) 28135
DNA damage checkpoint
centriole replication
reciprocal meiotic recombination
proteasomal protein catabolic process
signal transduction in response to DNA damage
innate immune response
meiotic telomere clustering
negative regulation of innate immune response
protein stabilization
spindle assembly
centrosome duplication
protein localization to centrosome
de novo centriole assembly
negative regulation of protein K63-linked ubiquitination
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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