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Invitrogen
ELP3 Polyclonal Antibody
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FIGURE: 1 / 6
ELP3 Antibody (PA5-103827) in IHC (P)
Immunohistochemistry analysis of ELP3 in human kidney cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ELP3 polyclonal antibody (Product # PA5-103827) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-103827
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ELP3(Accession Q9H9T3), corresponding to amino acid residues C99-R149.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ELP3.
Target Information
Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 2.3.1.48; elongation protein 3 homolog; Elongator complex protein 3; h KAT9; hELP3; rCG52086-like; tRNA uridine(34) acetyltransferase
Gene Aliases: 2610507P14Rik; ELP3; KAT9
UniProt ID: (Mouse) Q9CZX0
Entrez Gene ID: (Mouse) 74195, (Rat) 100362548
RNA polymerase II core binding
catalytic activity
histone acetyltransferase activity
N-acetyltransferase activity
phosphorylase kinase regulator activity
H3 histone acetyltransferase activity
H4 histone acetyltransferase activity
transferase activity
transferase activity, transferring acyl groups
metal ion binding
iron-sulfur cluster binding
DNA binding
histone modifying enzyme
neuron migration
tRNA wobble uridine modification
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
nervous system development
central nervous system development
histone acetylation
positive regulation of cell migration
histone H3 acetylation
histone H4 acetylation
regulation of protein kinase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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