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Invitrogen
UBE4B Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-104205
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human UBE4B(Accession O95155), corresponding to amino acid residues I9-N59.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total UBE4B.
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Homozygously deleted in neuroblastoma 1; RING-type E3 ubiquitin transferase E4 B; Ubiquitin conjugation factor E4 B; Ubiquitin fusion degradation protein 2; ubiquitination factor E4B, UFD2 homolog
基因别名: 4930551I19Rik; 4933406G05Rik; AU014668; D4Bwg0973e; HDNB1; KIAA0684; mKIAA0684; UBE4B; UFD2; UFD2a; Ufd2p
UniProt ID: (Mouse) Q9ES00
Entrez Gene ID: (Mouse) 63958
protein polyubiquitination
ventricular trabecula myocardium morphogenesis
ubiquitin-dependent protein catabolic process
protein monoubiquitination
granzyme-mediated apoptotic signaling pathway
response to UV
protein ubiquitination
neuron projection development
response to endoplasmic reticulum stress
proteasome-mediated ubiquitin-dependent protein catabolic process
cellular protein catabolic process
protein autoubiquitination
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