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Invitrogen
UROD Polyclonal Antibody
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UROD Antibody (PA5-104404) in IHC (P)
Immunohistochemistry analysis of UROD in human kidney cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with UROD polyclonal antibody (Product # PA5-104404) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-104404
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human UROD(Accession P06132), corresponding to amino acid residues E316-Q366.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total UROD.
靶标信息
This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: porphyrinogen carboxylase; UPD; URO D; URO-D; Uroporphyrinogen decarboxylase; uroporphyrinogen III decarboxylase
基因别名: AI323803; porphyrinogen carboxy-lyase; Uro-d; UROD
UniProt ID: (Mouse) P70697
Entrez Gene ID: (Mouse) 22275, (Rat) 29421
porphyrin-containing compound biosynthetic process
heme biosynthetic process
heme metabolic process
uroporphyrinogen III metabolic process
liver development
protoporphyrinogen IX biosynthetic process
response to iron ion
response to organic cyclic compound
response to amine
response to estradiol
response to ethanol
response to mercury ion
response to methylmercury
response to fungicide
cellular response to arsenic-containing substance
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
