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Invitrogen
DUS2L Polyclonal Antibody
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FIGURE: 1 / 10
DUS2L Antibody (PA5-104500) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded DUS2L in human kidney tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with DUS2L polyclonal antibody (Product # PA5-104500) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-104500
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DUS2(Accession Q9NX74), corresponding to amino acid residues C430-V480.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total DUS2L.
Target Information
Dihydrouridine synthase catalyzes reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA (Kato et al., 2005 [PubMed 15994936]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dihydrouridine synthase 2; hDUS2; tRNA-dihydrouridine synthase 2-like; tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Up-regulated in lung cancer protein 8; URLC8
Gene Aliases: 2310016K04Rik; DUS2; DUS2L; RGD1305612
UniProt ID: (Mouse) Q9D7B1
Entrez Gene ID: (Mouse) 66369, (Rat) 291978
RNA binding
double-stranded RNA binding
catalytic activity
protein kinase inhibitor activity
oxidoreductase activity
enoyl-[acyl-carrier-protein] reductase activity
tRNA dihydrouridine synthase activity
2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity
cis-2,3-dihydrodiol DDT dehydrogenase activity
trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity
cis-chlorobenzene dihydrodiol dehydrogenase activity
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity
trans-1,2-dihydrodiolphenanthrene dehydrogenase activity
3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity
benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity
benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity
citronellyl-CoA dehydrogenase activity
menthone dehydrogenase activity
phthalate 3,4-cis-dihydrodiol dehydrogenase activity
cinnamate reductase activity
flavin adenine dinucleotide binding
NADPH-dependent curcumin reductase activity
NADPH-dependent dihydrocurcumin reductase activity
RNA processing factor
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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