Search

  • Contact Us
  • Quick Order

Invitrogen

Phospho-NMDAR1 (Ser890) Polyclonal Antibody

View all (36) NMDAR1 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
Phospho-NMDAR1 (Ser890) Polyclonal Antibody

Product Details

PA5-104969

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human GRIN1(Accession Q05586), corresponding to amino acid residues around phosphorylated Ser890.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2816442

Product Specific Information

Antibody detects endogenous levels of NMDAR1 only when phosphorylated at Serine 890.

Target Information

NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: GluN1; Glun1r; Glutamate [NMDA] receptor subunit zeta-1; glutamate receptor; Glutamate receptor ionotropic, NMDA 1; N-methyl-D-aspartate glutamate receptor; N-methyl-D-aspartate receptor subunit NR1; neurotransmitter receptor; NMD-R1; NMDA R1 receptor C1 cassette; NMDA receptor 1; NMDZ1; NMZ1; NR1C1; NR1C2; NR1C2'; NR1N1; pGluN1; RP11-350O14.1

View more View less

Gene Aliases: GluN1; GluRdelta1; Glurz1; GluRzeta1; GRIN1; M100174; NMD-R1; Nmdar; NMDAR1; NR1; Rgsc174

View more View less

UniProt ID: (Rat) P35439, (Mouse) P35438

View more View less

Entrez Gene ID: (Rat) 24408, (Mouse) 14810

View more View less

Function(s)
ionotropic glutamate receptor activity NMDA glutamate receptor activity receptor binding extracellular-glutamate-gated ion channel activity cation channel activity calcium channel activity calcium ion binding protein binding calmodulin binding glycine binding glutamate binding enzyme binding voltage-gated cation channel activity glutamate receptor binding neurotransmitter binding protein heterodimerization activity protein dimerization activity receptor activity ion channel activity transmembrane signal receptor
Process(es)
conditioned taste aversion startle response suckling behavior response to amphetamine cation transport calcium ion transport cellular calcium ion homeostasis respiratory gaseous exchange learning or memory learning memory long-term memory associative learning adult locomotory behavior olfactory learning visual learning regulation of cell communication positive regulation of cell death response to organic cyclic compound response to amine propylene metabolic process sensory perception of pain pons maturation cerebral cortex development ion transmembrane transport regulation of ion transmembrane transport social behavior ionotropic glutamate receptor signaling pathway synaptic transmission, glutamatergic regulation of membrane potential positive regulation of apoptotic process response to morphine regulation of neuron apoptotic process negative regulation of neuron apoptotic process regulation of respiratory gaseous exchange response to ethanol positive regulation of transcription from RNA polymerase II promoter regulation of synaptic plasticity regulation of neuronal synaptic plasticity regulation of long-term neuronal synaptic plasticity rhythmic process regulation of dendrite morphogenesis regulation of axonogenesis neuromuscular process protein tetramerization response to calcium ion regulation of synapse assembly calcium ion homeostasis excitatory postsynaptic potential prepulse inhibition male mating behavior response to fungicide calcium ion transmembrane transport cellular response to manganese ion positive regulation of excitatory postsynaptic potential transport ion transport chemical synaptic transmission cation transmembrane transport
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support