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Invitrogen
Phospho-IKK gamma (Ser31) Polyclonal Antibody
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Phospho-IKK gamma (Ser31) Antibody (PA5-105045) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-IKK gamma (Ser31) in human testis tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-IKK gamma (Ser31) polyclonal antibody (Product # PA5-105045) using a dilution of 1:200 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-105045
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human IKBKG(Accession Q9Y6K9), corresponding to amino acid residues around phosphorylated Ser31.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of IKK gamma only when phosphorylated at Serine 31.
靶标信息
IKK gamma is the regulatory subunit of the inhibitor of the kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FIP-3; gikk; I-kappa-B kinase subunit gamma; IkB kinase-associated protein 1; IKK3; IKKAP1; Inhibitor of nuclear factor kappa-B kinase subunit gamma; mF; NEMO; NF-kappa-B essential modifier; NF-kappa-B essential modulator; OTTHUMP00000207079; OTTHUMP00000212188
基因别名: FIP3; IKBKG; NEMO
Entrez Gene ID: (Human) 8517
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