Search
Invitrogen
Phospho-CaMKI (Thr177) Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
{{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation']}}:
FIGURE: 1 / 4
Phospho-CaMKI (Thr177) Antibody (PA5-105644) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-CaMKI (Thr177) in mouse kidney tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-CaMKI (Thr177) polyclonal antibody (Product # PA5-105644) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-105644
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CAMK1(Accession Q14012), corresponding to amino acid residues around phosphorylated Thr177.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of CaMK1 alpha only when phosphorylated at Thr177.
Target Information
CAMK1 (CaMK1) is a serine/threonine kinase that is a member of the calcium/calmodulin-dependent protein kinase family. It is involved in cell differentiation, nervous system development, and signal transduction. CAMK1 is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: caM kinase I alpha; caM-KI; CAMK1-PEN; caMKI-alpha; G alpha interacting protein; MGC120317; MGC120318; regulator of G-protein signalling 19; unnamed protein product
Gene Aliases: Camk; CAMKI; CaMKIalpha; D6Ertd263e; Gaip
UniProt ID: (Human) Q14012, (Rat) Q63450, (Mouse) Q91YS8
Entrez Gene ID: (Human) 8536, (Rat) 171503, (Mouse) 52163
signal transduction
regulation of neuron projection development
positive regulation of neuron projection development
regulation of protein localization
intracellular signal transduction
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein export from nucleus
regulation of synapse organization
regulation of muscle cell differentiation
positive regulation of muscle cell differentiation
positive regulation of synapse structural plasticity
positive regulation of syncytium formation by plasma membrane fusion
positive regulation of dendritic spine development
protein phosphorylation
nucleocytoplasmic transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support