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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of MAP4 only when phosphorylated at Ser696.
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MAP 4; MAP-4; Microtubule-associated protein 4
基因别名: AA407148; MAP-4; MAP4; Mtap-4; Mtap4
UniProt ID: (Mouse) P27546, (Rat) Q5M7W5
Entrez Gene ID: (Mouse) 17758, (Rat) 367171