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Invitrogen
Phospho-SHC3 (Tyr424) Polyclonal Antibody
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Phospho-SHC3 (Tyr424) Antibody (PA5-106036) in ICC/IF
Immunocytochemistry analysis of Phospho-SHC3 (Tyr424) in Hela cells (serum starvation). The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Phospho-SHC3 (Tyr424) polyclonal antibody (Product # PA5-106036) 1:200 and mouse anti-beta tubulin antibody (1:200) for 1 hour at 37°C. An AlexaFluor594 conjugated goat ant... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-106036
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SHC3(Accession Q92529), corresponding to amino acid residues around phosphorylated Tyr424.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of Shc3 only when phosphorylated at Tyr424.
靶标信息
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: N-Shc; Neuronal Shc; Protein Rai; SH2 domain protein C3; SHC-transforming protein 3; SHC-transforming protein C; src homology 2 domain-containing transforming protein C3; Src homology 2 domain-containing-transforming protein C3
基因别名: N-Shc; NSHC; Rai; SHC3; SHCC
UniProt ID: (Mouse) Q61120
Entrez Gene ID: (Rat) 114858, (Mouse) 20418
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