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Invitrogen
Phospho-SRC1 (Thr1179) Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-106041
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NCOA1(Accession Q15788), corresponding to amino acid residues around phosphorylated Thr1179.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of KAT13A/SRC1 only when phosphorylated at Thr1179.
靶标信息
Clone 1135 recognizes SRC-1, steroid-receptor coactivator-1. SRC-1 is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activity. SRC-1 has a molecular weight of 160 kDa and has a basic helix-loop-helix (bHLH)-PAS domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ASV; bHLHe74; c-SRC; Class E basic helix-loop-helix protein 74; mNRC-1; NCoA-1; Nuclear receptor coactivator 1; Nuclear receptor coactivator protein 1; p60-Src; Protein Hin-2; Renal carcinoma antigen NY-REN-52; RIP160; SRC-1; SRC-1 (-Q); SRC-a/NCoA-1; Steroid receptor coactivator 1; steroid receptor coactivator-1
基因别名: BHLHE74; KAT13A; NCOA1; SRC-1; SRC1
UniProt ID: (Mouse) P70365
Entrez Gene ID: (Mouse) 17977
RNA polymerase II regulatory region DNA binding
DNA binding
chromatin binding
transcription coactivator activity
histone acetyltransferase activity
signal transducer activity
protein binding
transcription factor binding
transferase activity
transferase activity, transferring acyl groups
ligand-dependent nuclear receptor binding
enzyme binding
estrogen receptor binding
ligand-dependent nuclear receptor transcription coactivator activity
protein complex binding
progesterone receptor binding
nuclear hormone receptor binding
retinoic acid receptor binding
retinoid X receptor binding
protein dimerization activity
protein N-terminus binding
histone modifying enzyme
positive regulation of transcription from RNA polymerase II promoter by galactose
transcription, DNA-templated
regulation of transcription, DNA-templated
signal transduction
response to estradiol
response to retinoic acid
response to progesterone
cellular response to hormone stimulus
positive regulation of apoptotic process
histone H4 acetylation
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of female receptivity
positive regulation of transcription from RNA polymerase II promoter
male mating behavior
labyrinthine layer morphogenesis
regulation of nucleic acid-templated transcription
regulation of cellular response to drug
regulation of RNA biosynthetic process
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