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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total ARRDC3.
Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis of activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Arrestin domain-containing protein 3; Liver regeneration-related protein LRRG00048
基因别名: AI450344; Arrdc3; Kiaa1376; LRRGT00048; mKIAA1376
UniProt ID: (Rat) Q6TXF1, (Mouse) Q7TPQ9
Entrez Gene ID: (Rat) 309945, (Mouse) 105171