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Invitrogen
EGFL4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-106684
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MEGF8(Accession Q7Z7M0), corresponding to amino acid residues P1701-G1751.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total MEGF8.
Target Information
EGFL4 (epidermal growth factor-like protein 4), also known as MEGF8 (multiple epidermal growth factor-like domains protein 8) or C19orf49, is a 2,845 amino acid single-pass type I membrane protein. EGFL4 contains 2 CUB domains, 5 EGF-like domains, 12 Kelch repeats, 4 laminin EGF-like domains and 7 PSI domains. Existing as two alternatively spliced isoforms, the gene encoding EGFL4 maps to human chromosome 19q13.2. Chromosome 19 consists of approximately 63 million bases, makes up over 2% of human genomic DNA, and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EGF-like domain-containing protein 4; EGF-like protein 4; EGF-like-domain, multiple 4; epidermal growth factor-like protein 4; HBV pre-s2 binding protein 1; HBV pre-S2-binding protein 1; hepatitis B virus pre-S2-binding protein 1; multiple EGF-like domains protein 8; SBP1; unnamed protein product
Gene Aliases: b2b1702.2Clo; b2b1702Clo; b2b288Clo; C19orf49; CRPT2; EGFL4; m687Ddg; mKIAA0817; SBP1
UniProt ID: (Human) Q7Z7M0, (Mouse) P60882
Entrez Gene ID: (Human) 1954, (Mouse) 269878
in utero embryonic development
morphogenesis of an epithelium
embryonic heart tube morphogenesis
smoothened signaling pathway
determination of left/right symmetry
heart development
regulation of gene expression
protein ubiquitination
neurogenesis
embryonic limb morphogenesis
BMP signaling pathway
limb morphogenesis
aorta development
cell migration involved in gastrulation
embryonic digit morphogenesis
negative regulation of smoothened signaling pathway
embryonic morphogenesis
embryonic skeletal system morphogenesis
skeletal system morphogenesis
positive regulation of axon extension involved in axon guidance
epiboly involved in gastrulation with mouth forming second
limb development
embryonic heart tube left/right pattern formation
left/right pattern formation
coronary vasculature development
determination of heart left/right asymmetry
pharyngeal arch artery morphogenesis
protein-containing complex assembly
determination of digestive tract left/right asymmetry
craniofacial suture morphogenesis
fasciculation of sensory neuron axon
embryonic brain development
signal transduction
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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