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Invitrogen
ATIC Polyclonal Antibody
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ATIC Antibody (PA5-106931) in IHC (P)
Immunohistochemistry analysis of ATIC in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ATIC polyclonal antibody (Product # PA5-106931) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-106931
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ATIC(Accession P31939), corresponding to amino acid residues S563-H592.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total ATIC.
靶标信息
ATIC is a 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase which helps catalyze the penultimate and final steps of the de novo purine biosynthetic pathway. The human ATIC cDNA encodes a deduced 591-amino acid protein that is 81% identical to the chicken sequence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AICAR transformylase/inosine monophosphate cyclohydrolase; ATIC; Bifunctional purine biosynthesis protein ATIC; bifunctional purine biosynthesis protein PURH
基因别名: 2610509C24Rik; AA536954; ATIC; AW212393; OK/SW-cl.86; PURH
UniProt ID: (Rat) O35567, (Mouse) Q9CWJ9
Entrez Gene ID: (Rat) 81643, (Mouse) 108147
brainstem development
'de novo' IMP biosynthetic process
nucleoside metabolic process
cobalamin metabolic process
ribonucleotide metabolic process
response to inorganic substance
cerebellum development
cerebral cortex development
organ regeneration
dihydrofolate metabolic process
tetrahydrofolate biosynthetic process
purine nucleotide biosynthetic process
metabolic process
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