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Invitrogen
ANT1/ANT2/ANT3/ANT4 Polyclonal Antibody
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ANT1/ANT2/ANT3/ANT4 Antibody (PA5-109394) in IHC (P)
Immunohistochemistry analysis of ANT1/ANT2/ANT3/ANT4 in paraffin-embedded human colon carcinoma. Samples were incubated with ANT1/ANT2/ANT3/ANT4 Polyclonal antibody (Product # PA5-109394) using a dilution of 1:50 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-109394
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human ANT1 (NP_001142.2).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.65 mg/mL
规格
165 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GMLPDPKNVH IFVSWMIAQS VTAVAGLVSY PFDTVRRRMM MQSGRKGADI MYTGTVDCWR KIAKDEGAKA FFKGAWSNVL RGMGGAFVLV LYDEIKKYV
靶标信息
ANT1/2/3/4 (SLC25A4, SLC25A5, SLC25A6, SLC25A31) are members of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adenine nucleotid translocator 2 fibroblast isoform (ATP-ADP carrier protein); Adenine nucleotid translocator 2, fibroblast isoform (ATP-ADP carrier protein); adenine nucleotide translocase 4; adenine nucleotide translocase-1; Adenine nucleotide translocator 1; adenine nucleotide translocator 1 (skeletal muscle); adenine nucleotide translocator 1, skeletal muscle; Adenine nucleotide translocator 2; adenine nucleotide translocator 2 (fibroblast); adenine nucleotide translocator 2 fibroblast isoform (ATP-ADP carrier protein); adenine nucleotide translocator 2, fibroblast isoform (ATP-ADP carrier protein); Adenine nucleotide translocator 4; adenine nucleotide translocator), member 31; adenine nucleotide translocator), member 31-like; ADP,ATP carrier protein 1; ADP,ATP carrier protein 2; ADP,ATP carrier protein 4; ADP,ATP carrier protein, fibroblast isoform; ADP,ATP carrier protein, heart/skeletal muscle; ADP,ATP carrier protein, heart/skeletal muscle isoform T1; ADP.ATP translocase; ADP/ADT translocator protein; ADP/ATP carrier 1; ADP/ATP carrier protein; ADP/ATP translocase 1; ADP/ATP translocase 2; ADP/ATP translocase 4; ANT 1; ANT 2; ANT 4; heart/skeletal muscle ATP/ADP translocator; mANC1; mitochondrial adenine nucleotide translocator; Mitochondrial S-adenosylmethionine carrier protein; mitochondrial S-adenosylmethionine transporter; progressive external ophthalmoplegia 2; progressive external ophthalmoplegia 3; S-adenosylmethionine mitochondrial carrier protein; SAM carrier; solute carrier family 25 (mitochondrial adenine nucleotide translocator) member 4; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 31-like; solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) member 4 isoform SLC25A4_1; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) member 4 isoform SLC25A4_2; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) member 4 isoform SLC25A4_3; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 26; solute carrier family 25 (S-adenosylmethionine carrier), member 26; Solute carrier family 25 member 26; Solute carrier family 25 member 31; Solute carrier family 25 member 4; Solute carrier family 25 member 5; solute carrier family 25, member 26; Sperm flagellar energy carrier protein; SZFULLNAME2; unnamed protein product
基因别名: 1700034J06Rik; 2F1; 4930433D19Rik; 4933433F13Rik; AAC1; AAC2; AAC4; Anc1; ANT; ANT 1; ANT 4; ANT1; ANT2; ANT4; AU019225; AW557176; COXPD28; D6Bwg0781e; MTDPS12; MTDPS12A; PEO2; PEO3; PEOA2; SAMC; SFEC; SFEC35kDa; SLC25A26; SLC25A31; SLC25A4; SLC25A5; Slc25a6; SZGENESYMBOL2; T1; T2; T3
UniProt ID: (Human) Q70HW3, (Human) Q9H0C2, (Human) P12235, (Human) P05141, (Mouse) Q5U680, (Mouse) Q3V132, (Rat) Q05962, (Mouse) P48962, (Rat) Q09073, (Mouse) P51881
Entrez Gene ID: (Human) 115286, (Human) 83447, (Human) 291, (Human) 292, (Mouse) 67582, (Rat) 362403, (Rat) 689108, (Mouse) 73333, (Rat) 85333, (Mouse) 11739, (Rat) 25176, (Mouse) 11740
S-adenosyl-L-methionine transmembrane transporter activity
antiporter activity
S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity
ATP:ADP antiporter activity
protein binding
hydrogen ion transmembrane transporter activity
adenine transmembrane transporter activity
oxidative phosphorylation uncoupler activity
adenine nucleotide transmembrane transporter activity
RNA binding
ubiquitin protein ligase binding
transporter activity
enzyme binding
poly(A) RNA binding
mitochondrial carrier protein
transfer/carrier protein
ion transport
S-adenosyl-L-methionine transport
purine nucleoside transmembrane transport
macromolecule methylation
L-alpha-amino acid transmembrane transport
mitochondrial S-adenosyl-L-methionine transmembrane transport
male meiosis I
spermatogenesis
cell differentiation
regulation of mitochondrial membrane permeability
transmembrane transport
mitochondrial ADP transmembrane transport
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
mitochondrial ATP transmembrane transport
mitochondrial genome maintenance
generation of precursor metabolites and energy
apoptotic mitochondrial changes
adenine transport
ADP transport
negative regulation of necroptotic process
positive regulation of mitophagy
hydrogen ion transmembrane transport
adaptive thermogenesis
chromosome segregation
positive regulation of cell proliferation
B cell differentiation
erythrocyte differentiation
adenine nucleotide transport
cellular response to leukemia inhibitory factor
transport
S-adenosyl-L-methionine transmembrane transport
liver development
heart development
aging
negative regulation of cardiac muscle cell apoptotic process
positive regulation of cell growth involved in cardiac muscle cell development
response to interleukin-1
negative regulation of mitochondrial membrane permeability involved in apoptotic process
positive regulation of oxidative phosphorylation uncoupler activity
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