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Invitrogen
Brachyury Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-110455
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein containing a sequence corresponding to amino acids 226-435 of human Brachyury (NP_0031721)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.92 mg/mL
规格
192 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: HKEMMEEPGD SQQPGYSQWG WLLPGTSTLC PPANPHPQFG GALSLPSTHS CDRYPTLRSH RSSPYPSPYA HRNNSPTYSD NSPACLSMLQ SHDNWSSLGM PAHPSMLPVS HNASPPTSSS QYPSLWSVSN GAVTPGSQAA AVSNGLGAQF FRGSPAHYTP LTHPVSAPSS SGSPLYEGAA AATDIVDSQY DAAAQGRLIA SWTPVSPPSM
靶标信息
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: brachyury homolog; Brachyury protein; Protein T; RP11-459F1.1; T-box transcription factor T
基因别名: T; TBXT
Entrez Gene ID: (Rat) 292301
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor binding
RNA polymerase II activating transcription factor binding
transcriptional repressor activity, RNA polymerase II transcription factor binding
molecular_function
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
sequence-specific DNA binding
Rel homology transcription factor
negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
somitogenesis
neural plate morphogenesis
neural tube closure
heart morphogenesis
positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
penetration of zona pellucida
mesoderm development
mesoderm migration involved in gastrulation
positive regulation of cell proliferation
anatomical structure morphogenesis
anterior/posterior pattern specification
notochord formation
reproductive process
signal transduction involved in regulation of gene expression
BMP signaling pathway
notochord development
post-anal tail morphogenesis
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system development
canonical Wnt signaling pathway
bone morphogenesis
SMAD protein signal transduction
determination of heart left/right asymmetry
cellular response to retinoic acid
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