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Invitrogen
HSD17B1 Polyclonal Antibody
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FIGURE: 1 / 3
HSD17B1 Antibody (PA5-115383) in ICC/IF
Immunocytochemistry analysis of HSD17B1 in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115383) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-115383
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human HSD17B1(Accession P14061), corresponding to amino acid residues A290-Q328.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total HSD17B1.
Target Information
HSD17B1 is favors the reduction of estrogens and androgens. It also has 20-alpha-HSD activity. It uses preferentially NADH.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 17-beta-HSD 1; 20 alpha-hydroxysteroid dehydrogenase; estradiol 17-beta-dehydrogenase 1; placental 17-beta-hydroxysteroid dehydrogenase; placental 17-beta-hydroxysteroid dehydrogenase precursor (EC 1.1.1.62); short chain dehydrogenase/reductase family 28C member 1; short chain dehydrogenase/reductase family 28CE, member 1; unnamed protein product
Gene Aliases: 17-beta-HSD; 20-alpha-HSD; E2DH; EDH17B2; EDHB17; HSD17; SDR28C1
UniProt ID: (Human) P14061
Entrez Gene ID: (Human) 3292
estradiol 17-beta-dehydrogenase activity
steroid binding
protein binding
small molecule binding
protein homodimerization activity
testosterone dehydrogenase (NAD+) activity
testosterone 17-beta-dehydrogenase (NADP+) activity
NADP binding
NADP+ binding
17-beta-hydroxysteroid dehydrogenase (NADP+) activity
estradiol binding
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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