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Invitrogen
CHMP2A Polyclonal Antibody
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CHMP2A Antibody (PA5-119777) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded rat bladder tissue using CHMP2A Polyclonal Antibody (Product # PA5-119777). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the CHMP2A antibody at a dilution of... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-119777
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within N-terminal human CHMP2A.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: SW480 cell lysate, A431 cell lysate, HepG2 cell lysate, rat bladder tissue.
Subcellular Location: Late endosome membrane.
靶标信息
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A is required for both MVB formation and regulation of cell cycle progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Charged multivesicular body protein 2a; CHMP2a; chromatin modifying protein 2A; Chromatin-modifying protein 2a; mVps2; Putative breast adenocarcinoma marker BC-2; Vacuolar protein sorting-associated protein 2; Vacuolar protein sorting-associated protein 2-1; vacuolar protein-sorting-associated protein 2; Vps2-1
基因别名: 1500016L11Rik; BC2; CHMP2; CHMP2A; RGD1305050
UniProt ID: (Mouse) Q9DB34
Entrez Gene ID: (Rat) 365191, (Mouse) 68953
cell separation after cytokinesis
nucleus organization
vacuolar transport
mitotic metaphase plate congression
membrane invagination
regulation of centrosome duplication
viral budding via host ESCRT complex
establishment of protein localization
regulation of viral process
protein polymerization
protein homooligomerization
protein heterooligomerization
negative regulation of cell death
regulation of mitotic spindle assembly
positive regulation of viral release from host cell
positive regulation of exosomal secretion
negative regulation of centriole elongation
transport
protein transport
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