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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive test controls include: U-87MG, Mouse testis, Mouse kidney, Rat testis. The target is usually found in the following locations: Cytoplasm, Mitochondrion.
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Glutathione peroxidase 4; GPx-4; HGNC:4556; PHGPx; Phospholipid hydroperoxide glutathione peroxidase; Phospholipid hydroperoxide glutathione peroxidase GPX4; phospholipid hydroperoxide glutathione peroxidase, mitochondrial; phospholipid hydroperoxide glutathione peroxidase, nuclear; sperm nuclei glutathione peroxidase
基因别名: GPx-4; GPX4; GSHPx-4; mtPHGPx; PHGPx; snGPx
UniProt ID: (Mouse) O70325, (Rat) P36970
Entrez Gene ID: (Mouse) 625249, (Rat) 29328