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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive test controls include: A-549, HeLa, Raji, NCI-H460, Mouse heart, Mouse skeletal muscle, Mouse kidney, Rat brain. The target is usually found in the following locations: Cytoplasm, Nucleus matrix, cytoskeleton.
Immunogen sequence: MASGVTVNDE VIKVFNDMKV RKSSTQEEIK KRKKAVLFCL SDDKRQIIVE EAKQILVGDI GDTVEDPYTS FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: COF2; Cofilin, muscle isoform; Cofilin-2; HGNC:1875
基因别名: CFL2
UniProt ID: (Mouse) P45591
Entrez Gene ID: (Rat) 366624, (Mouse) 12632