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Invitrogen
AKR1B10 Polyclonal Antibody
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AKR1B10 Antibody (PA5-122255) in WB
Western blot analysis of AK1BA using AK1BA Polyclonal Antibody (Product # PA5-118936) at a dilution of 0.5 µg/mL. Lane 1: Rat Stomach lysate; Lane 2: Rat Small intestine lysate; Lane 3: A549 cell lysate; Lane 4: HepG2 cell lysate. Secondary antibody used is HRP-Goat anti-Rabbit IgG polyclonal antibody at a dilution of 0.2 µg/mL.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-122255
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein Aldose Reductase Like Protein 1. The antigen corresponds to amino acid range 1-316 of the target protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
AKR1B10, a 316aa protein, catalyzes efficient reduction ofaliphatic and aromatic aldehydes. It the first cytosolic NADP (H)-dependent retinal reductase described in humans and is characterized by the presence of a novel NADP binding motif. Due to its ability to convert glucose to sorbitol, AKR1B10 may have a role in development of secondary diabetic complications.It is abundantly expressed in adrenal gland, small intestine and colon, with lower levels in liver, thymus, prostate, testis, and skeletal muscle and its levels are up regulated in certain cancers such as hepatocellular carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Aldo-keto reductase family 1 member B10; Aldose reductase-like; Aldose reductase-related protein; ARL-1; ARP; MGC14103; SI reductase; Small intestine reductase
基因别名: AKR1B10; AKR1B11
Entrez Gene ID: (Rat) 296972
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
