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Invitrogen
CDw293 Polyclonal Antibody
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图: 1 / 3
CDw293 Antibody (PA5-141005) in ICC/IF
Immunocytochemistry analysis of BMPR1B in HepG2 cells (green). Samples were incubated in BMPR1B Polyclonal antibody (Product # PA5-141005). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-141005
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein within human BMPR1B aa 14-126.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4, with 40% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
BMPR1B (also known as ALK6, CDw293) is a member of the transmembrane serine/threonine kinase that is the member of the bone morphogenetic protein (BMP) receptor, which is closely related to the activin receptors, ACVR1 and ACVR2. BMPR1B is mainly involved in the endochondral bone formation and embryogenesis. BMPR1B expressed in normal and cancerous prostate tissues and used in the endocrine therapy that given to the prostate cancer patients. BMPR1B receptor trafficking also play a significant role in FOP pathogenesis and used in human T-cell differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activin receptor-like kinase 6; ALK-6; BMP type-1B receptor; Bone morphogenetic protein receptor type-1B; CDw293; Serine/threonine-protein kinase receptor R6; SKR6
基因别名: Acvrlk6; AI385617; ALK-6; Alk6; AV355320; BMPR-1B; BMPR-IB; BMPR1B; CFK-43a; SKR6
UniProt ID: (Mouse) P36898
Entrez Gene ID: (Mouse) 12167
nucleotide binding
glycoprotein binding
protein kinase activity
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
transforming growth factor beta-activated receptor activity
transforming growth factor beta receptor activity, type I
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
SMAD binding
metal ion binding
serine/threonine protein kinase receptor
skeletal system development
cartilage condensation
ovarian cumulus expansion
eye development
chondrocyte differentiation
protein phosphorylation
estrogen biosynthetic process
transmembrane receptor protein serine/threonine kinase signaling pathway
transforming growth factor beta receptor signaling pathway
dorsal/ventral pattern formation
phosphorylation
cell differentiation
positive regulation of bone mineralization
BMP signaling pathway
retinal ganglion cell axon guidance
limb morphogenesis
ovulation cycle
camera-type eye development
positive regulation of cell differentiation
positive regulation of osteoblast differentiation
cartilage development
retina development in camera-type eye
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
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