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Invitrogen
Kir6.2 (KCNJ11) Polyclonal Antibody
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Kir6.2 (KCNJ11) Antibody (PA5-18711) in IHC (P)
Immunohistochemistry analysis of Kir6.2 (KCNJ11) in human pancreas. Samples were incubated with Kir6.2 (KCNJ11) polyclonal antibody (Product # PA5-18711) using a dilution of 75 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-18711
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (ERRARFVSKKGNC) corresponding to the internal amino acids of Kcnj11 (aa 33-43).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with canine, mouse and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
靶标信息
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AI842722; ATP-sensitive inward rectifier potassium channel 11; AW491124; IKATP; Inward rectifier K(+) channel Kir6.2; IRK11; KATP; KATP channel; MGC133230; Potassium channel, inwardly rectifying subfamily J member 11
基因别名: KCNJ11
Entrez Gene ID: (Human) 3767
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