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Invitrogen
Rabex-5 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-21117
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 19 amino acid peptide near the center terminus of human RABEX5.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is rat brain tissue lysate.
PA5-21117 can be used with blocking peptide PEP-1231.
Target Information
RABGEF1 forms a complex with rabaptin-5 (RABPT5) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: RAB guanine nucleotide exchange factor (GEF) 1; Rab5 exchange factor; rabaptin-5-associated exchange factor for Rab5; rabex-5; Ras negative regulator Rabex-5; Ras negative regulator Rabex-5/Rin2; unnamed protein product
Gene Aliases: Rab5ef; rabex-5; RABEX5; RAP1; Rin2
UniProt ID: (Human) Q9UJ41, (Mouse) Q9JM13
Entrez Gene ID: (Human) 27342, (Mouse) 56715, (Rat) 360797
negative regulation of protein phosphorylation
negative regulation of leukocyte migration
protein targeting to membrane
vesicle-mediated transport
endosomal transport
negative regulation of interleukin-6 production
negative regulation of mast cell activation
negative regulation of mast cell degranulation
negative regulation of Ras protein signal transduction
negative regulation of receptor-mediated endocytosis
negative regulation of inflammatory response
regulation of Fc receptor mediated stimulatory signaling pathway
dendritic transport
negative regulation of Kit signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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