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Invitrogen
ALOX12B Polyclonal Antibody
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ALOX12B Antibody (PA5-23608) in IHC (P)
Immunohistochemistry analysis of ALOX12B in formalin fixed and paraffin embedded human tonsil tissue. Samples were incubated with ALOX12B polyclonal antibody (Product # PA5-23608) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-23608
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 622-652 amino acids from the C-terminal region of human ALOX12B
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2 mg/mL
规格
800 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with mouse and rat based on sequence homology.
靶标信息
This gene encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 12R-lipoxygenase; 12R-LOX; Arachidonate 12-lipoxygenase, 12R-type; Epidermis-type lipoxygenase 12
基因别名: 12R-LOX; ALOX12B; ARCI2
Entrez Gene ID: (Human) 242
arachidonate 12-lipoxygenase activity
iron ion binding
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
metal ion binding
arachidonate 8(R)-lipoxygenase activity
arachidonate 12(R)-lipoxygenase activity
linoleate 9S-lipoxygenase activity
protein lipidation
sphingolipid metabolic process
positive regulation of gene expression
arachidonic acid metabolic process
lipoxygenase pathway
lipid oxidation
positive regulation of MAPK cascade
linoleic acid metabolic process
ceramide biosynthetic process
hepoxilin biosynthetic process
establishment of skin barrier
positive regulation of mucus secretion
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